Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.40 |
| ▸ | NPC1 | O15118 | 10/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9948833 | 0.75 | RAB9A (0.43) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL706413 | 0.73 | ILK (0.46) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7410420 | 0.72 | RAB9A (0.48) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL15987793 | 0.71 | KDM4E (0.36) | KDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL29117998 | 0.68 | RAB9A (0.46) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5323085 | 0.68 | RAB9A (0.49) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL827403 | 0.68 | RAB9A (0.67) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL547704 | 0.67 | NPC1 (0.45) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4151986 | 0.67 | — | — | |
| Hydrogen Sulfide SCHEMBL16859912 | 0.66 | RAB9A (0.64) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140085-A1 | AZABICYCLOALKANES AS CCR5 MODULATORS | Pfizer Limited (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000038680-A1 | AZABICYCLOALKANES AS CCR5 MODULATORS | PFIZER LIMITED (GB) | 2000-07-06 | — | — | WO | disclosed |