Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 4/20 | 0.68 |
| ▸ | CPA3 | P15088 | 3/20 | 0.68 |
| ▸ | CPB1 | P15086 | 1/20 | 0.68 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL638640 | 0.87 | CPA1 (0.70) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL8399603 | 0.84 | CPA3 (0.66) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL1914987 | 0.84 | CPA1 (0.66) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL7289839 | 0.84 | CPA3 (0.66) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL7354310 | 0.84 | CPA3 (0.66) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL2398335 | 0.84 | CPA1 (0.66) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL901408 | 0.84 | CPA1 (0.66) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL9226958 | 0.83 | CPA3 (0.64) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL1915564 | 0.81 | CPA1 (1.00) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL393002 | 0.81 | CPA1 (1.00) | CPA1CPA3CPB1CPB2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366669-A1 | MALIC ACID DERIVATIVE CONTAINING RENIN INHIBITING PEPTIDES | THE UPJOHN COMPANY (US) | 1990-05-09 | — | — | EP | disclosed |
| WO-1989000161-A1 | MALIC ACID DERIVATIVE CONTAINING RENIN INHIBITING PEPTIDES | THE UPJOHN COMPANY (US) | 1989-01-12 | — | — | WO | disclosed |