Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP7 | P09237 | 4/20 | 0.58 |
| ▸ | BMP1 | P13497 | 11/20 | 0.57 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | MMP10 | P09238 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414985 | 0.96 | MMP7 (0.58) | MMP7BMP1MMP9NPY5RMMP10 | |
| SCHEMBL7410769 | 0.89 | NPY5R (0.61) | MMP7BMP1MMP9NPY5RMMP10 | |
| SCHEMBL7419448 | 0.87 | MMP7 (0.58) | MMP7BMP1MMP9NPY5RMMP10 | |
| SCHEMBL7413636 | 0.87 | MMP7 (0.53) | MMP7BMP1MMP9NPY5RMMP10 | |
| SCHEMBL7410576 | 0.86 | MMP7 (0.65) | MMP7MMP9NPY5RMMP10ADAM17 | |
| SCHEMBL7417246 | 0.85 | MMP7 (0.65) | MMP7BMP1MMP9MMP10MMP13 | |
| SCHEMBL7411422 | 0.83 | MMP7 (0.58) | MMP7BMP1MMP9NPY5RMMP10 | |
| SCHEMBL7408520 | 0.82 | MMP7 (0.53) | MMP7BMP1MMP9NPY5RMMP10 | |
| SCHEMBL7419926 | 0.81 | MMP7 (0.60) | MMP7BMP1MMP9MMP10MMP13 | |
| SCHEMBL7415839 | 0.80 | MMP7 (0.66) | MMP7BMP1MMP9MMP10MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218389-B1 | FOR THERAPY AND PROPHYLAXIS OF ARTHRITIS, CANCER, CARDIOVASCULAR DISORDERS; SKIN DISORDERS; OCULAR DISORDERS; INFLAMMATION AND GUM DISEASES, MULTIPLE SCLEROSIS, CACHEXIA, PREVENTING LOOSENING OF PROSTHETIC DEVICES | THE PROCTER & GAMBLE CO. | 2001-04-17 | — | — | US | disclosed |
| EP-1009737-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999006340-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |