Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444355 | 0.89 | MAPT (0.55) | PKMRAD52MAPTLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7433736 | 0.88 | MAPT (0.54) | PKMRAD52MAPTLMNASMN1; SMN2 | |
| SCHEMBL10886665 | 0.88 | PKM (0.61) | PKMRAD52MAPTLMNASMN1; SMN2 | |
| SCHEMBL7410880 | 0.86 | PDGFRB (0.49) | PKMRAD52MAPTLMNASMN1; SMN2 | |
| SCHEMBL10891860 | 0.81 | PKM (0.43) | PKMRAD52MAPTLMNACA1 | |
| SCHEMBL6420733 | 0.80 | MEN1 (0.52) | MAPTLMNACA1CA2MAPK1 | |
| SCHEMBL7439882 | 0.79 | ALDH1A1 (0.47) | PKMRAD52MAPTLMNASMN1; SMN2 | |
| SCHEMBL7436927 | 0.79 | PDE7A (0.46) | MAPTLMNAPDE10APDGFRBMEN1 | |
| SCHEMBL7427118 | 0.79 | MAPK1 (0.50) | MAPTLMNASMN1; SMN2HTTPDGFRB | |
| Nerisopam SCHEMBL1004757 | 0.78 | CYP1A2 (0.63) | PKMRAD52MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |