Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408771 | 0.86 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7407974 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7412441 | 0.82 | SRC (0.44) | KDM4EALDH1A1PKMMEN1KMT2A | |
| SCHEMBL7413021 | 0.82 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL4954775 | 0.80 | HPGD (0.53) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7412091 | 0.74 | GAA (0.49) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7411565 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL10472497 | 0.71 | KMT2A (0.59) | KDM4EALDH1A1HPGDHSD17B10PKM | |
| SCHEMBL30417213 | 0.71 | KMT2A (0.59) | KDM4EALDH1A1HPGDHSD17B10PKM | |
| SCHEMBL679127 | 0.71 | MAPT (0.61) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075021-A | 1H-pyrido[3,4-b]indole-4-carboxamide derivatives, preparation and application thereof in therapeutics | SYNTHELABO (FR) | 2000-06-13 | — | — | US | disclosed |