Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411667 | 1.00 | CTSS (0.53) | CTSSSYKMEN1KMT2AHTT | |
| SCHEMBL7158263 | 0.89 | CTSS (0.50) | CTSSSYKMEN1KMT2ACTSL | |
| SCHEMBL7158260 | 0.89 | CTSS (0.50) | CTSSSYKMEN1KMT2ACTSL | |
| SCHEMBL6666953 | 0.89 | CTSS (0.50) | CTSSSYKMEN1KMT2ACTSL | |
| SCHEMBL6664291 | 0.86 | CRHBP (0.52) | CTSSSYKMEN1KMT2ACTSL | |
| SCHEMBL7154604 | 0.84 | CTSS (0.46) | CTSSSYKMEN1KMT2ACTSL | |
| SCHEMBL7154600 | 0.84 | CTSS (0.46) | CTSSSYKMEN1KMT2ACTSL | |
| SCHEMBL29813445 | 0.84 | CTSS (0.51) | CTSSSYKMEN1KMT2AHTT | |
| SCHEMBL8381862 | 0.84 | CTSS (0.53) | CTSSSYKMEN1KMT2ACTSL | |
| SCHEMBL7158550 | 0.84 | CA1 (0.46) | CTSSSYKMEN1KMT2ACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200457-A2 | CYSTEINE PROTEASE INHIBITORS | Naeja Pharmaceutical Inc. (CA) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009169-A2 | CYSTEINE PROTEASE INHIBITORS | NAEJA PHARMACEUTICAL INC (CA) | 2001-02-08 | — | — | WO | disclosed |