Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.44 |
| ▸ | ACE | P12821 | 7/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.44 |
| ▸ | CPA1 | P15085 | 5/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413775 | 0.91 | PPARG (0.49) | MMEACEACE2CPA1PPARG | |
| SCHEMBL7413345 | 0.90 | MME (0.46) | MMEACEACE2CPA1PPARG | |
| SCHEMBL7407175 | 0.88 | MME (0.48) | MMEACEACE2CPA1PPARG | |
| SCHEMBL7308604 | 0.86 | MMEL1 (0.52) | — | |
| SCHEMBL7415659 | 0.84 | KMT2A (0.48) | MMEACEACE2CPA1KMT2A | |
| SCHEMBL7419794 | 0.84 | MME (0.50) | MMEGPR34MEN1KMT2A | |
| SCHEMBL7348038 | 0.82 | MME (0.51) | MMEACEACE2CPA1 | |
| SCHEMBL7322712 | 0.82 | MME (0.51) | MMEACEACE2CPA1 | |
| SCHEMBL31510352 | 0.81 | ANPEP (0.48) | MMEACEACE2CPA1ECE1 | |
| SCHEMBL7411238 | 0.81 | PPARG (0.48) | MMEACEACE2CPA1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660840-B1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | disclosed |
| US-5550119-A | ENDOTHELIN-CONVERTING ENZYM INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |
| US-5250522-A | Neutral endopeptidase inhibitors; cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |