Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | BACE1 | P56817 | 2/20 | 0.70 |
| ▸ | MAOB | P27338 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.65 |
| ▸ | RELA | Q04206 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10348519 | 1.00 | MAPT (0.71) | MAPTBACE1MAOBMEN1KMT2A | |
| SCHEMBL7412208 | 1.00 | MAPT (0.71) | MAPTBACE1MAOBMEN1KMT2A | |
| SCHEMBL11548851 | 0.86 | BACE1 (0.68) | MAPTBACE1MAOBMEN1KMT2A | |
| SCHEMBL11548849 | 0.86 | BACE1 (0.68) | MAPTBACE1MAOBMEN1KMT2A | |
| SCHEMBL7411297 | 0.84 | BACE1 (0.65) | MAPTBACE1MAOBMEN1KMT2A | |
| SCHEMBL10666396 | 0.84 | BACE1 (0.65) | MAPTBACE1MAOBMEN1KMT2A | |
| SCHEMBL42323 | 0.83 | MAPT (1.00) | MAPTBACE1MAOBMEN1KMT2A | |
| SCHEMBL820084 | 0.83 | MAPT (1.00) | MAPTBACE1MAOBMEN1KMT2A | |
| SCHEMBL10673342 | 0.83 | MAPT (1.00) | MAPTBACE1MAOBMEN1KMT2A | |
| SCHEMBL3295983 | 0.83 | MAPT (1.00) | MAPTBACE1MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126094-B1 | NEW 1,4-DIHYDROPYRIDINE ESTERS AND PREPARATION METHODS THEREOF AND DRUGS CONTAINING SAID ESTERS | CERMOL S.A. (CH) | 1990-06-20 | — | — | EP | disclosed |
| EP-0126094-A1 | NEW 1,4-DIHYDROPYRIDINE ESTERS AND PREPARATION METHODS THEREOF AND DRUGS CONTAINING SAID ESTERS. | CERMOL SA (CH) | 1984-11-28 | — | — | EP | disclosed |
| WO-1984002132-A1 | NEW 1,4-DIHYDROPYRIDINE ESTERS AND PREPARATION METHODS THEREOF AND DRUGS CONTAINING SAID ESTERS | CERMOL SA (CH) | 1984-06-07 | — | — | WO | disclosed |