Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406719 | 0.83 | HTR2A (0.53) | HTR6HTR2AHTR2CCYP1A2CYP2D6 | |
| SCHEMBL7410597 | 0.81 | HTR6 (0.57) | HTR6HTR2AHTR2CKDM4ETBXA2R | |
| SCHEMBL7412035 | 0.81 | HTR6 (0.55) | HTR6HTR2AHTR2CTBXA2RPTGDR | |
| SCHEMBL7410827 | 0.81 | PTGDR2 (0.54) | HTR6HTR2AHTR2CTBXA2RPTGDR | |
| SCHEMBL14492880 | 0.80 | HTR2A (0.47) | HTR6HTR2AHTR2CCYP1A2CYP2D6 | |
| SCHEMBL11421176 | 0.80 | DRD2 (0.50) | HTR6 | |
| SCHEMBL16559076 | 0.80 | HTR2A (0.53) | HTR6HTR2AHTR2CCYP1A2CYP2D6 | |
| SCHEMBL16559077 | 0.80 | HTR2A (0.53) | HTR6HTR2AHTR2CCYP1A2CYP2D6 | |
| SCHEMBL6529682 | 0.80 | HTR2A (0.53) | HTR6HTR2AHTR2CCYP1A2CYP2D6 | |
| SCHEMBL7409349 | 0.80 | HTR6 (0.56) | HTR6HTR2AHTR2CTBXA2RPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | claimed |
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |