Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.50 |
| ▸ | RB1 | P06400 | 4/20 | 0.49 |
| ▸ | HTR1B | P28222 | 3/20 | 0.48 |
| ▸ | HTR1D | P28221 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412246 | 0.86 | HTR1B (0.53) | KMT2ABAZ2BRB1HTR1BHTR1D | |
| SCHEMBL11576749 | 0.84 | KMT2A (0.65) | L3MBTL1KMT2ABAZ2BRB1HTR1B | |
| SCHEMBL7403681 | 0.83 | HTR1F (0.56) | L3MBTL1KMT2ABAZ2BRB1HTR1B | |
| SCHEMBL7409510 | 0.82 | SIRT1 (0.55) | KMT2ABAZ2BHTR1BHTR1DMEN1 | |
| SCHEMBL9334201 | 0.82 | HTR1B (0.69) | L3MBTL1KMT2ABAZ2BRB1HTR1B | |
| SCHEMBL14040265 | 0.82 | RB1 (0.48) | L3MBTL1KMT2ABAZ2BRB1HTR1B | |
| SCHEMBL4288837 | 0.82 | HTR1D (0.72) | KMT2ABAZ2BHTR1BHTR1DMEN1 | |
| SCHEMBL11845531 | 0.81 | SIRT1 (0.55) | L3MBTL1KMT2ABAZ2BHTR1BHTR1D | |
| SCHEMBL7029893 | 0.79 | AR (0.46) | L3MBTL1KMT2AHTR1BHTR1DMEN1 | |
| SCHEMBL7412220 | 0.79 | KMT2A (0.60) | KMT2AHTR1BHTR1DMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |