Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318310 | 0.90 | AVPR1A (0.54) | AVPR1ARAB9AGAAAVPR2 | |
| SCHEMBL7418830 | 0.90 | ALDH1A1 (0.53) | RAB9A | |
| SCHEMBL7412261 | 0.87 | AVPR2 (0.52) | AVPR1AAVPR2 | |
| SCHEMBL7410950 | 0.85 | AVPR2 (0.53) | AVPR1AAVPR2 | |
| SCHEMBL7414617 | 0.84 | MEN1 (0.51) | AVPR1ARAB9AAVPR2 | |
| SCHEMBL7415990 | 0.83 | AVPR2 (0.50) | AVPR1AAVPR2 | |
| SCHEMBL7331708 | 0.81 | AVPR2 (0.59) | AVPR1AAVPR2 | |
| SCHEMBL8317555 | 0.80 | AVPR2 (0.54) | AVPR1ARAB9AAVPR2 | |
| SCHEMBL8316362 | 0.80 | AVPR2 (0.48) | AVPR1AAVPR2 | |
| SCHEMBL7417033 | 0.80 | AVPR2 (0.56) | AVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843944-A | Tricyclic diazepine vasopressin antagonists and oxytocin antagonists | AMERICAN CYANAMID COMPANY (US) | 1998-12-01 | — | — | US | claimed |
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |
| US-5854237-A | Tricyclic diazepine vasopressin antagonists and oxytocin antagonists | AMERICAN CYANAMID COMPANY (US) | 1998-12-29 | — | — | US | disclosed |
| US-5843944-A | Tricyclic diazepine vasopressin antagonists and oxytocin antagonists | AMERICAN CYANAMID COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| US-5733905-A | CONGESTIVE HEART FAILURE; KIDNEY DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1998-03-31 | — | — | US | disclosed |