SCHEMBL741328

SCHEMBL741328

CC(C)(C)c1ccc(S(=O)(=O)c2ccc(C(C)(C)C)c(N=C=O)c2)cc1N=C=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.35
TRPA1 O75762 1/20 0.35
ALDH1A1 P00352 4/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 2/20 0.33
LMNA P02545 2/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GAA P10253 2/20 0.31
NR1I2 O75469 1/20 0.31
HSD11B1 P28845 1/20 0.31
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4912154 0.77 CYP3A4 (0.38) CYP3A4TRPA1ALDH1A1MAPTHPGD
SCHEMBL31425155 0.77 CYP3A4 (0.59) CYP3A4TRPA1ALDH1A1HPGDTSHR
SCHEMBL739692 0.77 CYP3A4 (0.59) CYP3A4TRPA1ALDH1A1MAPTHPGD
SCHEMBL2585906 0.77 CYP3A4 (0.59) CYP3A4TRPA1ALDH1A1HPGDTSHR
SCHEMBL9180347 0.75 ESRRA (0.39) CYP3A4TRPA1ALDH1A1MAPTHPGD
SCHEMBL15744782 0.74 POLB (0.42) CYP3A4ALDH1A1MAPTHPGDLMNA
SCHEMBL739522 0.74 MAPK1 (0.44) CYP3A4TRPA1ALDH1A1MAPTHPGD
SCHEMBL11191599 0.74 CYP3A4 (0.46) CYP3A4TRPA1ALDH1A1MAPTHPGD
SCHEMBL741260 0.73 MAPK1 (0.58) CYP3A4ALDH1A1HPGDLMNAPOLB
SCHEMBL11194024 0.71 RAD1 (0.36) CYP3A4TRPA1ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11767467-B2 Photochromic compound and curable composition containing said photochromic compound TOKUYAMA CORPORATION (JP) 2023-09-26 US disclosed
EP-2970554-B1 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG IND OHIO INC (US) 2023-09-20 EP disclosed
EP-3345954-B1 POLYROTAXANE, PRODUCTION METHOD THEREFOR, AND OPTICAL COMPOSITION CONTAINING SAID POLYROTAXANE TOKUYAMA CORP (JP) 2023-07-05 EP disclosed
US-20230120549-A1 Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same PPG INDUSTRIES OHIO, INC. 2023-04-20 US disclosed
EP-3653615-B1 CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING SAME, AND OPTICAL ARTICLE COMPRISING CURED PRODUCT FORMED OF CURABLE COMPOSITION TOKUYAMA CORP (JP) 2023-03-01 EP disclosed
US-11591436-B2 Polyurethane article and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2023-02-28 US disclosed
US-11578174-B2 Polyrotaxane, production method therefor, and optical composition containing said polyrotaxane TOKUYAMA CORPORATION (JP) 2023-02-14 US disclosed
US-20220119581-A1 Aircraft Windows PPG INDUSTRIES, INC. 2022-04-21 US disclosed
US-20220056170-A1 OPTICAL MATERIAL COMPOSITION AND OPTICAL MATERIAL TOKUYAMA CORPORATION (JP) 2022-02-24 US disclosed
US-11248083-B2 Aircraft windows PPG INDUSTRIES OHIO, INC. (US) 2022-02-15 US disclosed
EP-0505150-A1 Stabilizing method of isocyanate compounds and isocyanate compositions stabilized thereby MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-23 EP disclosed
US-5126388-A Sulfur-containing polyurethane or polythiourethane and internal mold release agent MITSUI TOATSU CHEMICALS, INC. (JP) 1992-06-30 US disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
US-5013496-A Polyurethane or polythiourethane MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
US-4946923-A S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-08-07 US disclosed
EP-0378895-A1 A mercapto compound, a high refractive index resin and lens and a process for preparing them MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-25 EP disclosed
US-4929707-A Polyurethane base lens resin, plastic lens comprising the resin and preparation method of the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-05-29 US disclosed
EP-0330363-A2 Highly-refractive plastic lens and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0329389-A2 Polyurethane base lens and its preparation method MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
EP-0329386-A2 S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed