SCHEMBL739692

SCHEMBL739692

Cc1ccc(S(=O)(=O)c2ccc(C)c(N=C=O)c2)cc1N=C=O

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.59
TRPA1 O75762 1/20 0.59
ALDH1A1 P00352 9/20 0.48
LMNA P02545 5/20 0.48
POLB P06746 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 1/20 0.42
GAA P10253 2/20 0.39
TDP1 Q9NUW8 2/20 0.37
TSHR P16473 2/20 0.36
MAPK1 P28482 1/20 0.36
HPGD P15428 1/20 0.36
PKM P14618 1/20 0.36
RAPGEF4 Q8WZA2 2/20 0.35
HTT P42858 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
SFRP1 Q8N474 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4096072 0.87 CYP3A4 (0.58) CYP3A4TRPA1ALDH1A1LMNASMN1; SMN2
SCHEMBL11278919 0.86 CYP3A4 (0.56) CYP3A4TRPA1ALDH1A1LMNAMAPT
SCHEMBL11191599 0.85 CYP3A4 (0.46) CYP3A4TRPA1ALDH1A1LMNAPOLB
SCHEMBL5653049 0.84 CYP3A4 (0.54) CYP3A4TRPA1ALDH1A1LMNATDP1
SCHEMBL13556579 0.82 CYP3A4 (0.51) CYP3A4TRPA1ALDH1A1LMNAGAA
SCHEMBL14125810 0.80 TRPA1 (0.57) CYP3A4TRPA1ALDH1A1LMNAPOLB
SCHEMBL739522 0.78 MAPK1 (0.44) CYP3A4TRPA1ALDH1A1LMNAPOLB
SCHEMBL741328 0.77 CYP3A4 (0.35) CYP3A4TRPA1ALDH1A1LMNAPOLB
SCHEMBL741260 0.77 MAPK1 (0.58) CYP3A4ALDH1A1LMNAPOLBSMN1; SMN2
SCHEMBL30163034 0.77 CA12 (0.53) CYP3A4TRPA1ALDH1A1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970554-B1 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG IND OHIO INC (US) 2023-09-20 EP disclosed
EP-3345954-B1 POLYROTAXANE, PRODUCTION METHOD THEREFOR, AND OPTICAL COMPOSITION CONTAINING SAID POLYROTAXANE TOKUYAMA CORP (JP) 2023-07-05 EP disclosed
US-20230120549-A1 Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same PPG INDUSTRIES OHIO, INC. 2023-04-20 US disclosed
US-11591436-B2 Polyurethane article and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2023-02-28 US disclosed
US-11578174-B2 Polyrotaxane, production method therefor, and optical composition containing said polyrotaxane TOKUYAMA CORPORATION (JP) 2023-02-14 US disclosed
US-20220119581-A1 Aircraft Windows PPG INDUSTRIES, INC. 2022-04-21 US disclosed
US-20220056170-A1 OPTICAL MATERIAL COMPOSITION AND OPTICAL MATERIAL TOKUYAMA CORPORATION (JP) 2022-02-24 US disclosed
US-11248083-B2 Aircraft windows PPG INDUSTRIES OHIO, INC. (US) 2022-02-15 US disclosed
EP-3936905-A1 TRANSPARENT PLASTIC SUBSTRATE AND PLASTIC LENS Hoya Lens Thailand Ltd. (TH) 2022-01-12 EP disclosed
EP-3936904-A1 TRANSPARENT PLASTIC SUBSTRATE AND PLASTIC LENS Hoya Lens Thailand Ltd. (TH) 2022-01-12 EP disclosed
US-5191055-A Polythiourethanes MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-02 US disclosed
EP-0506315-A2 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-30 EP disclosed
EP-0505150-A1 Stabilizing method of isocyanate compounds and isocyanate compositions stabilized thereby MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-23 EP disclosed
US-5126388-A Sulfur-containing polyurethane or polythiourethane and internal mold release agent MITSUI TOATSU CHEMICALS, INC. (JP) 1992-06-30 US disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
US-5013496-A Polyurethane or polythiourethane MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
US-4946923-A S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-08-07 US disclosed
EP-0378895-A1 A mercapto compound, a high refractive index resin and lens and a process for preparing them MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-25 EP disclosed
US-4929707-A Polyurethane base lens resin, plastic lens comprising the resin and preparation method of the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-05-29 US disclosed
EP-0329389-A2 Polyurethane base lens and its preparation method MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed