SCHEMBL739522

SCHEMBL739522

O=C=Nc1cc(S(=O)(=O)c2ccc(Cl)c(N=C=O)c2)ccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 4/20 0.44
TDP1 Q9NUW8 2/20 0.44
CYP3A4 P08684 4/20 0.39
ALDH1A1 P00352 3/20 0.39
MAPT P10636 2/20 0.35
TRPA1 O75762 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
HPGD P15428 1/20 0.33
POLB P06746 2/20 0.32
GAA P10253 1/20 0.32
TSHR P16473 1/20 0.32
SLC16A1 P53985 1/20 0.32
LMNA P02545 2/20 0.32
VCAM1 P19320 1/20 0.32
PKM P14618 1/20 0.32
HTR6 P50406 1/20 0.32
CA12 O43570 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11194630 0.85 MAPK1 (0.40) MAPK1TDP1CYP3A4ALDH1A1MAPT
SCHEMBL739692 0.78 CYP3A4 (0.59) MAPK1TDP1CYP3A4ALDH1A1MAPT
SCHEMBL785906 0.76 TDP1 (0.50) MAPK1TDP1CYP3A4ALDH1A1MAPT
SCHEMBL29507682 0.76 TDP1 (0.50) MAPK1TDP1CYP3A4ALDH1A1MAPT
SCHEMBL49899 0.75 TDP1 (0.70) MAPK1TDP1CYP3A4ALDH1A1MAPT
SCHEMBL29365125 0.75 TDP1 (0.70) MAPK1TDP1CYP3A4ALDH1A1MAPT
SCHEMBL11197847 0.74 GAA (0.44) MAPK1TDP1CYP3A4ALDH1A1MAPT
SCHEMBL11191599 0.74 CYP3A4 (0.46) MAPK1TDP1CYP3A4ALDH1A1MAPT
SCHEMBL741328 0.74 CYP3A4 (0.35) MAPK1TDP1CYP3A4ALDH1A1MAPT
SCHEMBL741260 0.74 MAPK1 (0.58) MAPK1TDP1CYP3A4ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110869355-B Benzopyran compound, curable composition containing the compound, and optical article containing cured product formed from the curable composition 株式会社德山 2023-11-14 CN disclosed
US-11767467-B2 Photochromic compound and curable composition containing said photochromic compound TOKUYAMA CORPORATION (JP) 2023-09-26 US disclosed
EP-2970554-B1 POLYURETHANES, ARTICLES AND COATINGS PREPARED THEREFROM AND METHODS OF MAKING THE SAME PPG IND OHIO INC (US) 2023-09-20 EP disclosed
EP-3345954-B1 POLYROTAXANE, PRODUCTION METHOD THEREFOR, AND OPTICAL COMPOSITION CONTAINING SAID POLYROTAXANE TOKUYAMA CORP (JP) 2023-07-05 EP disclosed
US-20230120549-A1 Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same PPG INDUSTRIES OHIO, INC. 2023-04-20 US disclosed
EP-3653615-B1 CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING SAME, AND OPTICAL ARTICLE COMPRISING CURED PRODUCT FORMED OF CURABLE COMPOSITION TOKUYAMA CORP (JP) 2023-03-01 EP disclosed
US-11591436-B2 Polyurethane article and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2023-02-28 US disclosed
US-11578174-B2 Polyrotaxane, production method therefor, and optical composition containing said polyrotaxane TOKUYAMA CORPORATION (JP) 2023-02-14 US disclosed
US-20220119581-A1 Aircraft Windows PPG INDUSTRIES, INC. 2022-04-21 US disclosed
US-20220056170-A1 OPTICAL MATERIAL COMPOSITION AND OPTICAL MATERIAL TOKUYAMA CORPORATION (JP) 2022-02-24 US disclosed
EP-0528590-A1 Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-02-24 EP disclosed
EP-0505150-A1 Stabilizing method of isocyanate compounds and isocyanate compositions stabilized thereby MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-23 EP disclosed
US-5126388-A Sulfur-containing polyurethane or polythiourethane and internal mold release agent MITSUI TOATSU CHEMICALS, INC. (JP) 1992-06-30 US disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
US-5013496-A Polyurethane or polythiourethane MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
US-4946923-A S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-08-07 US disclosed
EP-0378895-A1 A mercapto compound, a high refractive index resin and lens and a process for preparing them MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-25 EP disclosed
US-4929707-A Polyurethane base lens resin, plastic lens comprising the resin and preparation method of the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-05-29 US disclosed
EP-0329389-A2 Polyurethane base lens and its preparation method MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
EP-0329386-A2 S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed