Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416311 | 0.87 | GPR119 (0.56) | GPR119KDM4EPKMFAAHHTR6 | |
| SCHEMBL4151572 | 0.83 | TGFBR1 (0.53) | GPR119KDM4EPKMFAAHTGFBR1 | |
| SCHEMBL7280689 | 0.82 | GPR119 (0.51) | GPR119KDM4EPKMFAAHHTR6 | |
| SCHEMBL7413661 | 0.81 | GPR119 (0.57) | GPR119KDM4EPKMFAAHHTR6 | |
| SCHEMBL7279210 | 0.80 | GPR119 (0.49) | GPR119KDM4EPKMFAAHHTR6 | |
| SCHEMBL4152000 | 0.80 | KDM4E (0.49) | GPR119KDM4EPKMFAAHTGFBR1 | |
| SCHEMBL8696526 | 0.80 | GPR119 (0.58) | GPR119KDM4EPKMFAAHHTR6 | |
| SCHEMBL5778797 | 0.79 | KDM4E (0.48) | GPR119KDM4EPKMFAAHTGFBR1 | |
| SCHEMBL4151836 | 0.79 | PDE4D (0.50) | GPR119KDM4EPKMFAAHTGFBR1 | |
| SCHEMBL30663176 | 0.79 | GPR119 (0.57) | GPR119KDM4EPKMFAAHHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880136-A | PREVENTING THROMBUS FORMATION | MERCK & CO., INC. (US) | 1999-03-09 | — | — | US | disclosed |
| US-5814643-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1998-09-29 | — | — | US | disclosed |