Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.51 |
| ▸ | YAP1 | P46937 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279210 | 0.88 | GPR119 (0.49) | GPR119YAP1KDM4EPKMTGFBR1 | |
| SCHEMBL7280692 | 0.83 | GPR119 (0.62) | GPR119YAP1FAAH | |
| SCHEMBL7280338 | 0.83 | GPR119 (0.51) | GPR119YAP1TGFBR1HTR6 | |
| SCHEMBL7282950 | 0.83 | STS (0.52) | GPR119YAP1KDM4EPKMTGFBR1 | |
| SCHEMBL7280754 | 0.82 | GPR119 (0.48) | GPR119YAP1TGFBR1HTR6SCN9A | |
| SCHEMBL7413655 | 0.82 | GPR119 (0.57) | GPR119KDM4EPKMTGFBR1HTR6 | |
| SCHEMBL7416311 | 0.81 | GPR119 (0.56) | GPR119KDM4EPKMTGFBR1HTR6 | |
| SCHEMBL7279787 | 0.80 | ITGB3 (0.47) | GPR119YAP1TGFBR1HTR6SCN9A | |
| SCHEMBL7273552 | 0.79 | YAP1 (0.48) | GPR119YAP1 | |
| SCHEMBL7442789 | 0.78 | STS (0.51) | GPR119YAP1KDM4EPKMHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040317-A | AN ANTIAGGLOMERANTS USEFUL IN THE PREVENTION AND TREATMENT OF DISEASES CAUSED BY THROMBUS FORMATION | MERCK & CO., INC. (US) | 2000-03-21 | — | — | US | disclosed |
| EP-0743302-B1 | Sulfonamide fibrinogen receptor antagonists | MERCK & CO INC (US) | 1999-08-04 | — | — | EP | disclosed |
| US-5658929-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0478363-B1 | Novel sulfonamide fibrinogen receptor antagonists | MERCK & CO INC (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0743302-A2 | Sulfonamide fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1996-11-20 | — | — | EP | disclosed |
| US-5292756-A | Novel sulfonamide fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1994-03-08 | — | — | US | disclosed |
| WO-1993019046-A1 | NOVEL SULFONAMIDE FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1993-09-30 | — | — | WO | disclosed |
| EP-0478363-A2 | Novel sulfonamide fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-04-01 | — | — | EP | disclosed |