Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.59 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | MC5R | P33032 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415439 | 0.77 | MCHR1 (0.72) | MCHR1 | |
| SCHEMBL31612499 | 0.71 | KMT2A (0.66) | MCHR1OPRL1FAAHKMT2AMC4R | |
| SCHEMBL27999347 | 0.69 | KMT2A (0.89) | OPRL1FAAHKMT2AMC4RMC5R | |
| SCHEMBL1681868 | 0.68 | MCHR1 (0.55) | MCHR1OPRL1FAAHKMT2AMC4R | |
| SCHEMBL23142619 | 0.68 | PKM (0.72) | OPRL1FAAHKMT2AMC4RMC5R | |
| SCHEMBL7412259 | 0.68 | MCHR1 (0.71) | MCHR1 | |
| Hydrochloric Acid SCHEMBL1681972 | 0.68 | MCHR1 (0.54) | MCHR1OPRL1FAAHKMT2AMC4R | |
| SCHEMBL7069999 | 0.67 | MC4R (0.72) | OPRL1FAAHKMT2AMC4RMC5R | |
| SCHEMBL21044068 | 0.66 | KMT2A (0.71) | MCHR1FAAHKMT2AMC4RMC5R | |
| SCHEMBL3602106 | 0.66 | KMT2A (0.71) | FAAHKMT2AMC4RMC5RPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |