Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HK1 | P19367 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509211 | 0.91 | ALOX5 (0.47) | ALOX5TSHRMAPTELANEKDM4E | |
| SCHEMBL7414503 | 0.86 | ALDH1A1 (0.49) | ALOX5TSHRMAPTELANEKDM4E | |
| SCHEMBL7407583 | 0.82 | ALOX5 (0.44) | ALOX5TSHRMAPTELANEKDM4E | |
| SCHEMBL7407581 | 0.82 | ALOX5 (0.44) | ALOX5TSHRMAPTELANEKDM4E | |
| SCHEMBL4615959 | 0.81 | TSHR (0.53) | ALOX5TSHRMAPTELANEKDM4E | |
| SCHEMBL8689904 | 0.79 | TSHR (0.48) | ALOX5TSHRMAPTELANEKDM4E | |
| SCHEMBL8689246 | 0.79 | MAPT (0.48) | ALOX5TSHRMAPTELANEKDM4E | |
| SCHEMBL3926579 | 0.79 | TSHR (0.46) | ALOX5TSHRMAPTELANEKDM4E | |
| SCHEMBL7511323 | 0.77 | ALDH1A1 (0.50) | ALOX5TSHRMAPTELANEKDM4E | |
| SCHEMBL7413507 | 0.76 | SMN1; SMN2 (0.46) | ALOX5TSHRMAPTELANEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075021-A | 1H-pyrido[3,4-b]indole-4-carboxamide derivatives, preparation and application thereof in therapeutics | SYNTHELABO (FR) | 2000-06-13 | — | — | US | disclosed |