Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511323 | 0.91 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4EHSD17B10ALOX15 | |
| SCHEMBL7413720 | 0.86 | ALOX5 (0.47) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL7750525 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EHSD17B10ALOX15 | |
| SCHEMBL7387558 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EHSD17B10ALOX15 | |
| SCHEMBL8688754 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4EHSD17B10ALOX15 | |
| SCHEMBL8687719 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4EHSD17B10ALOX15 | |
| SCHEMBL8687098 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4EHSD17B10ALOX15 | |
| SCHEMBL3923885 | 0.79 | ALOX15 (0.47) | ALDH1A1HPGDKDM4EHSD17B10ALOX15 | |
| SCHEMBL7509211 | 0.77 | ALOX5 (0.47) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL28026378 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4EHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075021-A | 1H-pyrido[3,4-b]indole-4-carboxamide derivatives, preparation and application thereof in therapeutics | SYNTHELABO (FR) | 2000-06-13 | — | — | US | disclosed |