Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535245 | 0.78 | HTR2A (0.36) | DPP4 | |
| SCHEMBL10361924 | 0.75 | ALDH1A1 (0.44) | IDO1CA1CA2CA7CA9 | |
| SCHEMBL6981619 | 0.71 | IDO1 (0.38) | IDO1TDO2CA1CA2CA7 | |
| SCHEMBL2451125 | 0.67 | NFE2L2 (0.50) | — | |
| SCHEMBL3899639 | 0.67 | NFE2L2 (0.50) | — | |
| SCHEMBL3540663 | 0.66 | IDO1 (0.41) | IDO1TDO2CA1CA2CA7 | |
| SCHEMBL20187377 | 0.66 | IDO1 (0.41) | IDO1TDO2CA1CA2CA7 | |
| SCHEMBL10584516 | 0.65 | AOC3 (0.39) | IDO1TDO2AOC3SLC6A2SLC6A4 | |
| SCHEMBL2549442 | 0.64 | IDO1 (0.39) | IDO1TDO2PTPN1AOC3HDAC3 | |
| SCHEMBL7129754 | 0.63 | IDO1 (0.48) | IDO1TDO2PTPN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250537-A | Treating psychoses | SCIOS NOVA INC. (US) | 1993-10-05 | — | — | US | disclosed |