Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 4/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | HTR1A | P08908 | 6/20 | 0.40 |
| ▸ | DRD1 | P21728 | 6/20 | 0.40 |
| ▸ | DRD4 | P21917 | 6/20 | 0.40 |
| ▸ | DRD5 | P21918 | 6/20 | 0.40 |
| ▸ | DRD3 | P35462 | 6/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413949 | 1.00 | CARM1 (0.42) | CARM1PRMT6UBE2MDCUN1D1DRD2 | |
| SCHEMBL7424918 | 0.89 | SLC6A5 (0.44) | CARM1PRMT6CCR2 | |
| SCHEMBL7424897 | 0.89 | SLC6A5 (0.44) | CARM1PRMT6CCR2 | |
| SCHEMBL7424905 | 0.89 | SLC6A5 (0.44) | CARM1PRMT6CCR2 | |
| SCHEMBL7417311 | 0.87 | KCNH2 (0.44) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL7417320 | 0.87 | KCNH2 (0.44) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL7469196 | 0.87 | KCNH2 (0.44) | DRD2HTR1ADRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL8718323 | 0.86 | KCNH2 (0.43) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL7417117 | 0.82 | CARM1 (0.41) | CARM1PRMT6UBE2MDCUN1D1DRD2 | |
| SCHEMBL7418312 | 0.82 | CARM1 (0.41) | CARM1PRMT6UBE2MDCUN1D1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328917-A | Aminoalkyl and phenyl substituted hydrogenated pyridines | NOVO NORDISK A/S (DK) | 1994-07-12 | — | — | US | disclosed |
| WO-1992001672-A1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-02-06 | — | — | WO | disclosed |