Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 5/20 | 0.41 |
| ▸ | DRD1 | P21728 | 5/20 | 0.41 |
| ▸ | DRD4 | P21917 | 5/20 | 0.41 |
| ▸ | DRD5 | P21918 | 5/20 | 0.41 |
| ▸ | DRD3 | P35462 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417311 | 1.00 | KCNH2 (0.44) | KCNH2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL7469196 | 1.00 | KCNH2 (0.44) | KCNH2HTR1ADRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL8718323 | 0.99 | KCNH2 (0.43) | KCNH2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL7424905 | 0.88 | SLC6A5 (0.44) | — | |
| SCHEMBL7424918 | 0.88 | SLC6A5 (0.44) | — | |
| SCHEMBL7424897 | 0.88 | SLC6A5 (0.44) | — | |
| SCHEMBL7413951 | 0.87 | CARM1 (0.42) | HTR1ADRD1DRD4DRD5DRD3 | |
| SCHEMBL7413949 | 0.87 | CARM1 (0.42) | HTR1ADRD1DRD4DRD5DRD3 | |
| SCHEMBL7466670 | 0.85 | BCHE (0.48) | HTR2ABCHEDRD2 | |
| SCHEMBL7466673 | 0.85 | BCHE (0.48) | HTR2ABCHEDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558487-B1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1998-10-07 | — | — | EP | claimed |
| EP-0558487-B1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1998-10-07 | — | — | EP | disclosed |
| US-5328917-A | Aminoalkyl and phenyl substituted hydrogenated pyridines | NOVO NORDISK A/S (DK) | 1994-07-12 | — | — | US | disclosed |
| WO-1992001672-A1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-02-06 | — | — | WO | disclosed |