Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424905 | 1.00 | SLC6A5 (0.44) | SLC6A5CARM1PRMT6CCR3CCR2 | |
| SCHEMBL7424918 | 1.00 | SLC6A5 (0.44) | SLC6A5CARM1PRMT6CCR3CCR2 | |
| SCHEMBL7413949 | 0.89 | CARM1 (0.42) | CARM1PRMT6CCR2 | |
| SCHEMBL7413951 | 0.89 | CARM1 (0.42) | CARM1PRMT6CCR2 | |
| SCHEMBL7417311 | 0.88 | KCNH2 (0.44) | — | |
| SCHEMBL7417320 | 0.88 | KCNH2 (0.44) | — | |
| SCHEMBL7469196 | 0.88 | KCNH2 (0.44) | — | |
| Hydrochloric Acid SCHEMBL8718323 | 0.87 | KCNH2 (0.43) | — | |
| SCHEMBL7417117 | 0.83 | CARM1 (0.41) | CARM1PRMT6CCR3 | |
| SCHEMBL7415105 | 0.83 | CARM1 (0.41) | CARM1PRMT6CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558487-B1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1998-10-07 | — | — | EP | disclosed |
| US-5328917-A | Aminoalkyl and phenyl substituted hydrogenated pyridines | NOVO NORDISK A/S (DK) | 1994-07-12 | — | — | US | disclosed |
| EP-0558487-A1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992001672-A1 | PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-02-06 | — | — | WO | disclosed |