Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 6/20 | 0.53 |
| ▸ | F2 | P00734 | 3/20 | 0.52 |
| ▸ | PLG | P00747 | 3/20 | 0.52 |
| ▸ | PLAU | P00749 | 3/20 | 0.52 |
| ▸ | PLAT | P00750 | 3/20 | 0.52 |
| ▸ | KLK8 | O60259 | 2/20 | 0.52 |
| ▸ | F10 | P00742 | 2/20 | 0.52 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.52 |
| ▸ | KLK1 | P06870 | 1/20 | 0.52 |
| ▸ | KLK2 | P20151 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414348 | 1.00 | CASP1 (0.53) | CASP1F2PLGPLAUPLAT | |
| SCHEMBL7414413 | 1.00 | CASP1 (0.53) | CASP1F2PLGPLAUPLAT | |
| SCHEMBL7414657 | 0.93 | FOLH1 (0.53) | F2PLGPLAUPLATKLK8 | |
| SCHEMBL7417654 | 0.93 | FOLH1 (0.53) | F2PLGPLAUPLATKLK8 | |
| SCHEMBL7415256 | 0.93 | FOLH1 (0.53) | F2PLGPLAUPLATKLK8 | |
| SCHEMBL7417445 | 0.90 | F2 (0.54) | F2PLGPLAUPLATKLK8 | |
| SCHEMBL7417435 | 0.90 | F2 (0.54) | F2PLGPLAUPLATKLK8 | |
| SCHEMBL7425557 | 0.85 | ITGB3 (0.62) | F10ITGB3ITGA2B | |
| SCHEMBL7425539 | 0.85 | ITGB3 (0.62) | F10ITGB3ITGA2B | |
| SCHEMBL7417659 | 0.85 | MEN1 (0.56) | F2PLGPLAUPLATKLK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | claimed |
| WO-1993012074-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-06-24 | — | — | WO | claimed |
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |
| WO-1993012074-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-06-24 | — | — | WO | disclosed |