Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.62 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425557 | 1.00 | ITGB3 (0.62) | ITGB3ITGA2BGRIA1PRSS1TMPRSS15 | |
| SCHEMBL8995532 | 0.93 | ITGB3 (0.56) | ITGB3ITGA2BGRIA1PRSS1F10 | |
| SCHEMBL7416798 | 0.93 | ITGB3 (0.56) | ITGB3ITGA2BGRIA1PRSS1F10 | |
| SCHEMBL7431042 | 0.92 | ITGB3 (0.70) | ITGB3ITGA2BPRSS1TMPRSS15F10 | |
| SCHEMBL7414342 | 0.85 | CASP1 (0.53) | ITGB3ITGA2BF10 | |
| SCHEMBL7414413 | 0.85 | CASP1 (0.53) | ITGB3ITGA2BF10 | |
| SCHEMBL7414348 | 0.85 | CASP1 (0.53) | ITGB3ITGA2BF10 | |
| SCHEMBL7323153 | 0.83 | ITGB3 (0.65) | ITGB3ITGA2B | |
| SCHEMBL7421070 | 0.82 | ITGB3 (0.55) | ITGB3ITGA2BGRIA1LMNATSHR | |
| SCHEMBL7421065 | 0.82 | ITGB3 (0.55) | ITGB3ITGA2BGRIA1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | claimed |
| WO-1993012074-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-06-24 | — | — | WO | claimed |
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |