Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7414269 | 0.79 | CHRNB2 (0.45) | KDM4ECXCR1CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL27489539 | 0.78 | ALDH1A1 (0.41) | — | |
| SCHEMBL7463943 | 0.77 | CHRNB2 (0.43) | KDM4ECXCR1CHRNB4CHRNA3CHRNA7 | |
| Hydrochloric Acid SCHEMBL7667687 | 0.77 | CHRNB4 (0.34) | CXCR1CHRNB4CHRNA3CHRNA7 | |
| Hydrochloric Acid SCHEMBL7416361 | 0.77 | ALDH1A1 (0.40) | — | |
| SCHEMBL7414509 | 0.76 | CHRNB4 (0.33) | CXCR1CHRNB4CHRNA3CHRNA7 | |
| Hydrochloric Acid SCHEMBL7664433 | 0.75 | CHRNB4 (0.33) | KDM4EKMT2ACXCR1CHRNB4CHRNA3 | |
| SCHEMBL7413674 | 0.74 | TSHR (0.36) | KDM4EKMT2AMEN1L3MBTL1CHRNB4 | |
| Hydrochloric Acid SCHEMBL7671102 | 0.73 | AKT1 (0.33) | CHRNB4CHRNA3CHRNA7 | |
| Hydrochloric Acid SCHEMBL7670028 | 0.73 | CHRNA3 (0.31) | CXCR1CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047690-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999032480-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1999-07-01 | — | — | WO | disclosed |