SCHEMBL7414818

SCHEMBL7414818

O=S(=O)(O)c1ccccc1-c1ccncc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
NPC1 O15118 2/20 0.47
TP53 P04637 1/20 0.47
MAPT P10636 1/20 0.47
RAB9A P51151 1/20 0.47
MAPK10 P53779 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HSD17B10 Q99714 1/20 0.47
NAMPT P43490 6/20 0.45
NOTUM Q6P988 1/20 0.41
HTR6 P50406 2/20 0.40
MAPK14 Q16539 1/20 0.40
PTGS2 P35354 1/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
IDO1 P14902 2/20 0.38
TDO2 P48775 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
PGAM1 P18669 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22534535 1.00 ALDH1A1 (0.47) ALDH1A1NPC1TP53MAPTRAB9A
SCHEMBL17888508 0.84 NPC1 (0.44) ALDH1A1NPC1TP53MAPTRAB9A
SCHEMBL29743050 0.84 CASP1 (0.47) ALDH1A1SMN1; SMN2HSD17B10MAPK14PTGS2
SCHEMBL232659 0.84 CASP1 (0.47) ALDH1A1SMN1; SMN2HSD17B10MAPK14PTGS2
SCHEMBL19742955 0.82 CCNC (0.40) ALDH1A1NPC1TP53MAPTRAB9A
Lithium SCHEMBL3173875 0.82 CASP1 (0.46) ALDH1A1SMN1; SMN2HSD17B10MAPK14PTGS2
SCHEMBL28934633 0.82 CASP1 (0.46) ALDH1A1SMN1; SMN2HSD17B10MAPK14PTGS2
SCHEMBL29194067 0.82 CASP1 (0.46) ALDH1A1SMN1; SMN2HSD17B10MAPK14PTGS2
Hydrochloric Acid SCHEMBL11757790 0.82 CASP1 (0.46) ALDH1A1SMN1; SMN2HSD17B10MAPK14PTGS2
Water SCHEMBL27371066 0.82 CASP1 (0.46) ALDH1A1SMN1; SMN2HSD17B10MAPK14PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118295212-A Composition for forming resist underlayer film containing glycol structure 日产化学株式会社 2024-07-05 CN disclosed
CN-115698857-A Resist underlayer film forming composition containing diol structure 日产化学株式会社 2023-02-03 CN disclosed
CN-114402009-A Liquid medicine resistant protective film containing polycarboxylic acid 日产化学株式会社 2022-04-26 CN disclosed
CN-113646352-A Composition for forming chemical-resistant protective film containing polymer having hydroxyaryl terminal 日产化学株式会社 2021-11-12 CN disclosed
CN-113574085-A Composition for forming chemical-resistant protective film containing polymer product having diol structure at terminal 日产化学株式会社 2021-10-29 CN disclosed
CN-105849642-B Resist underlayer film forming composition containing copolymer having triazine ring and sulfur atom in main chain 日产化学工业株式会社 2019-06-11 CN disclosed
CN-105849642-A Resist underlayer film forming composition containing copolymer having triazine ring and sulfur atom in main chain 日产化学工业株式会社 2016-08-10 CN disclosed
EP-0853618-A4 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE POULENC RORER PHARMA (US) 2000-03-15 EP disclosed
US-5958918-A Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds RHONE-POULENC RORER PHARMACEUTICALS INC. 1999-09-28 US disclosed
EP-0853618-A1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1998-07-22 EP disclosed
WO-1996040679-A1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) 1996-12-19 WO disclosed