Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | C5 | P01031 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414814 | 0.84 | ALDH1A1 (0.55) | KMT2AMAPTMEN1NPC1L3MBTL1 | |
| SCHEMBL7372874 | 0.84 | NAMPT (0.57) | KMT2AMAPTMEN1NPC1L3MBTL1 | |
| SCHEMBL7377053 | 0.81 | KMT2A (0.53) | KMT2AMAPTMEN1NPC1L3MBTL1 | |
| SCHEMBL8499797 | 0.81 | NAMPT (0.49) | MAPTNPC1NPSR1NAMPTALDH1A1 | |
| SCHEMBL7377969 | 0.79 | KMT2A (0.51) | KMT2AMAPTMEN1NPC1L3MBTL1 | |
| SCHEMBL8497486 | 0.77 | MAPT (0.46) | KMT2AMAPTMEN1NPC1NPSR1 | |
| SCHEMBL7379154 | 0.75 | PLAU (0.55) | KMT2AMAPTMEN1L3MBTL1HTT | |
| SCHEMBL7377976 | 0.75 | KMT2A (0.48) | KMT2AMAPTMEN1NPC1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9235167 | 0.74 | MEN1 (0.52) | KMT2AMAPTMEN1NPC1L3MBTL1 | |
| SCHEMBL9238430 | 0.73 | KMT2A (0.51) | KMT2AMAPTMEN1NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891325-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036859-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | disclosed |