Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | MMP3 | P08254 | 10/20 | 0.48 |
| ▸ | MMP1 | P03956 | 6/20 | 0.46 |
| ▸ | MMP13 | P45452 | 4/20 | 0.46 |
| ▸ | PDE4A | P27815 | 5/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BMP1 | P13497 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414840 | 0.82 | SLC1A3 (0.46) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL7414842 | 0.82 | SLC1A3 (0.46) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL7422337 | 0.79 | MMP2 (0.62) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL7422335 | 0.79 | MMP2 (0.62) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL6723870 | 0.73 | MMP2 (0.41) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL7383552 | 0.73 | ADAMTS4 (0.61) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL7383553 | 0.73 | ADAMTS4 (0.61) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL6075462 | 0.72 | MMP2 (0.53) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL6323453 | 0.72 | MMP2 (0.73) | MMP2MMP9MMP3MMP1MMP13 | |
| SCHEMBL6323452 | 0.72 | MMP2 (0.73) | MMP2MMP9MMP3MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218389-B1 | FOR THERAPY AND PROPHYLAXIS OF ARTHRITIS, CANCER, CARDIOVASCULAR DISORDERS; SKIN DISORDERS; OCULAR DISORDERS; INFLAMMATION AND GUM DISEASES, MULTIPLE SCLEROSIS, CACHEXIA, PREVENTING LOOSENING OF PROSTHETIC DEVICES | THE PROCTER & GAMBLE CO. | 2001-04-17 | — | — | US | disclosed |