Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 11/20 | 0.45 |
| ▸ | ACE | P12821 | 8/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 8/20 | 0.45 |
| ▸ | CPA1 | P15085 | 6/20 | 0.43 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.42 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322712 | 0.81 | MME (0.51) | MMEACEACE2CPA1SRR | |
| SCHEMBL7348038 | 0.81 | MME (0.51) | MMEACEACE2CPA1SRR | |
| SCHEMBL7407175 | 0.80 | MME (0.48) | MMEACEACE2CPA1SRR | |
| SCHEMBL7410339 | 0.79 | MME (0.45) | MMEACEACE2CPA1GPR34 | |
| SCHEMBL7408519 | 0.78 | MAPT (0.49) | MMEACEACE2CPA1GPR34 | |
| SCHEMBL7413312 | 0.78 | MME (0.45) | MMEACEACE2CPA1SRR | |
| SCHEMBL7411123 | 0.78 | MME (0.62) | MMEACEACE2CPA1ECE1 | |
| SCHEMBL7411127 | 0.78 | MME (0.62) | MMEACEACE2CPA1ECE1 | |
| SCHEMBL3103119 | 0.77 | FPR2 (0.54) | MMEACEACE2CPA1ECE1 | |
| SCHEMBL8921718 | 0.76 | ECE1 (0.45) | MMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660840-B1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | disclosed |
| US-5550119-A | ENDOTHELIN-CONVERTING ENZYM INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |
| EP-0660840-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES. | CIBA GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994005677-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1994-03-17 | — | — | WO | disclosed |
| US-5250522-A | Neutral endopeptidase inhibitors; cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |