Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 18/20 | 1.00 |
| ▸ | TPSD1 | Q9BZJ3 | 18/20 | 1.00 |
| ▸ | TPSG1 | Q9NRR2 | 18/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.71 |
| ▸ | F2 | P00734 | 6/20 | 0.71 |
| ▸ | PLG | P00747 | 2/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420536 | 0.85 | TPSAB1 (0.74) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7422609 | 0.82 | TPSAB1 (0.83) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7422920 | 0.80 | TPSAB1 (0.74) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7428430 | 0.76 | TPSAB1 (1.00) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7426287 | 0.74 | TPSAB1 (0.75) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7422450 | 0.72 | TPSAB1 (0.82) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7469000 | 0.72 | TPSAB1 (1.00) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| Hydrochloric Acid SCHEMBL7425867 | 0.71 | TPSAB1 (0.80) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| Hydrochloric Acid SCHEMBL7958973 | 0.71 | TPSAB1 (0.80) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7422621 | 0.70 | TPSAB1 (0.67) | TPSAB1TPSD1TPSG1PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782571-A1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL INFLAMMATORY CONDITION | ARRIS PHARMACEUTICAL CORPORATION (US) | 1997-07-09 | — | — | EP | claimed |
| WO-1996009297-A1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL INFLAMMATORY CONDITION | ARRIS PHARMACEUTICAL CORPORATION (US) | 1996-03-28 | — | — | WO | claimed |
| US-6211228-B1 | COMPOUNDS WITH AMINO, GUANIDINO AND AMIDINO HETEROCYCLIC COMPOUNDS | AXYS PHARMACEUTICALS, INC | 2001-04-03 | — | — | US | disclosed |