Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 19/20 | 0.83 |
| ▸ | TPSD1 | Q9BZJ3 | 19/20 | 0.83 |
| ▸ | TPSG1 | Q9NRR2 | 19/20 | 0.83 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.74 |
| ▸ | F2 | P00734 | 3/20 | 0.74 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.72 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.72 |
| ▸ | PLG | P00747 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469000 | 0.91 | TPSAB1 (1.00) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7422450 | 0.91 | TPSAB1 (0.82) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| Hydrochloric Acid SCHEMBL7958973 | 0.89 | TPSAB1 (0.80) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| Hydrochloric Acid SCHEMBL7425867 | 0.89 | TPSAB1 (0.80) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7416220 | 0.84 | TPSAB1 (1.00) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7415218 | 0.82 | TPSAB1 (0.77) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7415237 | 0.82 | TPSAB1 (1.00) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7420536 | 0.82 | TPSAB1 (0.74) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7428254 | 0.80 | TPSAB1 (0.73) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7962495 | 0.80 | TPSAB1 (0.73) | TPSAB1TPSD1TPSG1PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782571-A1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL INFLAMMATORY CONDITION | ARRIS PHARMACEUTICAL CORPORATION (US) | 1997-07-09 | — | — | EP | claimed |
| WO-1996009297-A1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL INFLAMMATORY CONDITION | ARRIS PHARMACEUTICAL CORPORATION (US) | 1996-03-28 | — | — | WO | claimed |