Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415428 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HPGDAPOBEC3GTAS1R3TAS1R1 | |
| SCHEMBL5567651 | 0.87 | POLB (0.51) | TAS1R3TAS1R1TSHRMEN1KMT2A | |
| SCHEMBL5567648 | 0.87 | POLB (0.51) | TAS1R3TAS1R1TSHRMEN1KMT2A | |
| SCHEMBL5735485 | 0.85 | PDE4B (0.52) | ALDH1A1HPGDAPOBEC3GTAS1R3TAS1R1 | |
| SCHEMBL5735482 | 0.85 | PDE4B (0.52) | ALDH1A1HPGDAPOBEC3GTAS1R3TAS1R1 | |
| SCHEMBL5735847 | 0.85 | TAS1R3 (0.48) | ALDH1A1HPGDAPOBEC3GTAS1R3TAS1R1 | |
| SCHEMBL5735842 | 0.85 | TAS1R3 (0.48) | ALDH1A1HPGDAPOBEC3GTAS1R3TAS1R1 | |
| SCHEMBL6167355 | 0.84 | PDE4B (0.53) | ALDH1A1HPGDAPOBEC3GTAS1R3TAS1R1 | |
| SCHEMBL5734204 | 0.84 | PDE4B (0.53) | ALDH1A1HPGDAPOBEC3GTAS1R3TAS1R1 | |
| SCHEMBL5734199 | 0.84 | PDE4B (0.53) | ALDH1A1HPGDAPOBEC3GTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163226-A1 | POLYSUBSTITUTED 6-PHENYLPHENANTHRIDINES WITH PDE-IV INHIBITING ACTIVITY | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000042018-A1 | POLYSUBSTITUTED 6-PHENYLPHENANTHRIDINES WITH PDE-IV INHIBITING ACTIVITY | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-07-20 | — | — | WO | disclosed |