Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KDM5C | P41229 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28742783 | 0.86 | LMNA (0.42) | LMNAALDH1A1CYP1A2GABRR1TSHR | |
| SCHEMBL28455132 | 0.85 | LMNA (0.46) | LMNAALDH1A1CYP1A2GABRR1TSHR | |
| SCHEMBL29405740 | 0.77 | LMNA (0.42) | LMNAEGLN1ALKBH5SUCNR1PHF8 | |
| SCHEMBL11406977 | 0.76 | — | — | |
| Heptanoate SCHEMBL27591538 | 0.76 | GPR84 (0.57) | LMNAALDH1A1CYP2C19CYP1A2TSHR | |
| SCHEMBL8199567 | 0.75 | — | — | |
| SCHEMBL3175734 | 0.74 | NOS3 (0.52) | EGLN1PHF8KDM2AKDM5CNOS3 | |
| Hydrochloric Acid SCHEMBL11409292 | 0.73 | GRIN2D (0.30) | ALDH1A1 | |
| Bromide SCHEMBL7533244 | 0.73 | TDP1 (0.36) | LMNAKDM4ECYP2C19TSHRBLM | |
| SCHEMBL7747710 | 0.73 | LMNA (0.42) | LMNAEGLN1ALKBH5SUCNR1PHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1097580-C | Aminoguanidine carboxylates for the treatment of non-insulin dependent diabetes mellitus | BIOVITRUM AB (SE) | 2003-01-01 | — | — | CN | disclosed |
| CN-1377642-A | Use of compound for preparing medicine for curing and preventing non-insulin dependent diabetes or obesity | BIOVITRUM AB (SE) | 2002-11-06 | — | — | CN | disclosed |
| CN-1164226-A | Aminoguanidine carboxylates for the treatment of non-insulin dependent diabetes mellitus | UPJOHN CO (US) | 1997-11-05 | — | — | CN | disclosed |
| US-5382568-A | Regulating release of prolactin and luteinizing hormone | ARIZONA BOARD OF REGENTS (US) | 1995-01-17 | — | — | US | disclosed |
| WO-1993003752-A1 | DECAPEPTIDE HAVING DOPAMINE STIMULATING ACTIVITY | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 1993-03-04 | — | — | WO | disclosed |