Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414392 | 0.99 | CHRM3 (0.53) | CHRM3OPRM1OPRD1OPRK1LMNA | |
| SCHEMBL1428246 | 0.99 | CHRM3 (0.53) | CHRM3OPRM1OPRD1OPRK1LMNA | |
| SCHEMBL1428238 | 0.89 | OPRM1 (0.44) | CHRM3OPRM1OPRD1OPRK1LMNA | |
| SCHEMBL7425414 | 0.87 | TP53 (0.58) | LMNATP53GAA | |
| SCHEMBL244317 | 0.85 | OPRM1 (0.43) | OPRM1OPRD1OPRK1LMNASLC22A1 | |
| SCHEMBL7421543 | 0.84 | OPRM1 (0.47) | OPRM1OPRD1OPRK1LMNASLC22A1 | |
| Hydrochloric Acid SCHEMBL8112617 | 0.82 | ALDH1A1 (0.67) | CHRM3LMNASLC22A1TSHRPRCP | |
| SCHEMBL1038462 | 0.82 | CHRM3 (0.60) | CHRM3LMNASLC6A4TSHRTP53 | |
| SCHEMBL8189527 | 0.80 | LMNA (0.41) | CHRM3OPRM1OPRD1LMNASLC6A4 | |
| SCHEMBL2987228 | 0.80 | CHRM3 (0.54) | CHRM3LMNATSHRTP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995002596-A1 | AZACYCLIC-HETEROCYCLIC COMPOUNDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-01-26 | — | — | WO | disclosed |