Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497984 | 0.88 | CYP2C19 (0.43) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL7415885 | 0.79 | SLC1A3 (0.46) | ALDH1A1CA1CA2LMNASLC1A3 | |
| SCHEMBL3392200 | 0.77 | ALDH1A1 (0.54) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL20446842 | 0.74 | ALDH1A1 (0.48) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL5996499 | 0.74 | ALDH1A1 (0.48) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL258423 | 0.71 | CA12 (0.49) | ALDH1A1CA1CA2LMNAPOLB | |
| SCHEMBL8557255 | 0.71 | ALDH1A1 (0.51) | ALDH1A1CA1CA2KMT2AL3MBTL1 | |
| SCHEMBL27713867 | 0.71 | F2 (0.50) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL634085 | 0.70 | ALDH1A1 (0.79) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL5031614 | 0.70 | MMP2 (0.46) | MMP1MMP2MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821241-A | INHIBIT BINDING OF FIBRINOGEN TO BLOOD PLATELETS, INHIBIT AGGREGATION OF BLOOD PLATELETS, PREVENT OR TREAT THROMBUS OR EMBOLUS FORMATION | MERCK & CO., INC. (US) | 1998-10-13 | — | — | US | disclosed |
| WO-1994018981-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-09-01 | — | — | WO | disclosed |