Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5995571 | 0.80 | HDAC3 (0.48) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL6255018 | 0.79 | GHSR (0.46) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL6255022 | 0.79 | GHSR (0.46) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL3392200 | 0.79 | ALDH1A1 (0.54) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL27713867 | 0.76 | F2 (0.50) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL7984352 | 0.75 | BCHE (0.47) | ALDH1A1MMP1MMP2MMP9MMP13 | |
| SCHEMBL7415883 | 0.74 | ALDH1A1 (0.46) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL7981503 | 0.73 | EGFR (0.43) | ALDH1A1MMP1MMP2MMP9MMP13 | |
| SCHEMBL634085 | 0.73 | ALDH1A1 (0.79) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL10282879 | 0.72 | ALDH1A1 (0.56) | ALDH1A1CA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060142586-A1 | Synthesis of 2-alkyl amino acids | CHORGHADE MUKUND S | 2006-06-29 | — | — | US | disclosed |
| US-7038073-B2 | Synthesis of 2-alkyl amino acids | GENZYME CORPORATION (US) | 2006-05-02 | — | — | US | disclosed |
| EP-1529037-A2 | SYNTHESIS OF 2-ALKYLCYSTEINES, 2-(HYDROXYLATED PHENYL)-4-ALKYLTHIAZOLINE-4-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | Genzyme Corporation (US) | 2005-05-11 | — | — | EP | disclosed |
| US-20040006224-A1 | Synthesis of 2-alkyl amino acids | GENZYME CORPORATION | 2004-01-08 | — | — | US | disclosed |
| WO-2003097622-A2 | SYNTHESIS OF 2-ALKYLCYSTEINES, 2-(HYDROXYLATED PHENYL)-4-ALKYLTHIAZOLINE-4-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | GENZYME CORPORATION (US) | 2003-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142586-A1 | Synthesis of 2-alkyl amino acids | ASNS, AAAS, FTH1 | ALDH1A1 2435/4885CA1 728/4885CA2 250/4885 |
| US-20040006224-A1 | Synthesis of 2-alkyl amino acids | ASNS, AAAS, FTH1 | ALDH1A1 2435/4885CA1 728/4885CA2 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.