Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 12/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.51 |
| ▸ | PDE4A | P27815 | 7/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416126 | 1.00 | PDE4B (0.51) | PDE4BPDE4DPDE4APDE4CPOLB | |
| SCHEMBL7366340 | 0.84 | PDE4B (0.56) | PDE4BPDE4DPDE4APDE4CPOLB | |
| SCHEMBL5351550 | 0.83 | PDE4B (0.55) | PDE4BPDE4DPDE4APDE4CPOLB | |
| SCHEMBL5351545 | 0.83 | PDE4B (0.55) | PDE4BPDE4DPDE4APDE4CPOLB | |
| SCHEMBL7938329 | 0.81 | GAA (0.60) | PDE4BPDE4DPDE4APDE4CPOLB | |
| SCHEMBL5362920 | 0.81 | PDE4B (0.56) | PDE4BPDE4DPDE4APDE4CPOLB | |
| SCHEMBL5362912 | 0.81 | PDE4B (0.56) | PDE4BPDE4DPDE4APDE4CPOLB | |
| SCHEMBL7435309 | 0.80 | PDE4B (0.53) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL8069537 | 0.80 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4CPOLB | |
| SCHEMBL7447001 | 0.80 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4CPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187817-A1 | CATHECOL HYDRAZONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Cheil Jedang Corporation (KR) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000073280-A1 | CATHECOL HYDRAZONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CHEIL JEDANG CORPORATION (KR) | 2000-12-07 | — | — | WO | disclosed |