Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 1/20 | 0.55 |
| ▸ | ANPEP | P15144 | 2/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416137 | 1.00 | SLC15A1 (0.55) | SLC15A1ANPEPERAP1ERAP2TAAR1 | |
| SCHEMBL7416141 | 1.00 | SLC15A1 (0.55) | SLC15A1ANPEPERAP1ERAP2TAAR1 | |
| SCHEMBL3131714 | 1.00 | SLC15A1 (0.55) | SLC15A1ANPEPERAP1ERAP2TAAR1 | |
| Hydrochloric Acid SCHEMBL7363138 | 0.98 | SLC15A1 (0.54) | SLC15A1ANPEPERAP1ERAP2TAAR1 | |
| Hydrochloric Acid SCHEMBL7363137 | 0.98 | SLC15A1 (0.54) | SLC15A1ANPEPERAP1ERAP2TAAR1 | |
| Hydrochloric Acid SCHEMBL7363142 | 0.98 | SLC15A1 (0.54) | SLC15A1ANPEPERAP1ERAP2TAAR1 | |
| Trifluoroacetic Acid SCHEMBL9943876 | 0.91 | SLC15A1 (0.51) | SLC15A1ANPEPERAP1ERAP2TAAR1 | |
| Trifluoroacetic Acid SCHEMBL9102768 | 0.91 | SLC15A1 (0.51) | SLC15A1ANPEPERAP1ERAP2TAAR1 | |
| Trifluoroacetic Acid SCHEMBL9102789 | 0.91 | SLC15A1 (0.51) | SLC15A1ANPEPERAP1ERAP2TAAR1 | |
| SCHEMBL2348815 | 0.88 | ERAP1 (0.47) | SLC15A1ANPEPERAP1ERAP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817778-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996030353-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1996-10-03 | — | — | WO | disclosed |