Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.42 |
| ▸ | ANPEP | P15144 | 3/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 5/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 3/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9102768 | 1.00 | SLC15A1 (0.51) | SLC15A1CTSLERAP1ANPEPERAP2 | |
| Trifluoroacetic Acid SCHEMBL9943876 | 1.00 | SLC15A1 (0.51) | SLC15A1CTSLERAP1ANPEPERAP2 | |
| SCHEMBL7416137 | 0.91 | SLC15A1 (0.55) | SLC15A1CTSLERAP1ANPEPERAP2 | |
| SCHEMBL3131714 | 0.91 | SLC15A1 (0.55) | SLC15A1CTSLERAP1ANPEPERAP2 | |
| SCHEMBL7416145 | 0.91 | SLC15A1 (0.55) | SLC15A1CTSLERAP1ANPEPERAP2 | |
| SCHEMBL7416141 | 0.91 | SLC15A1 (0.55) | SLC15A1CTSLERAP1ANPEPERAP2 | |
| Hydrochloric Acid SCHEMBL7363138 | 0.90 | SLC15A1 (0.54) | SLC15A1CTSLERAP1ANPEPERAP2 | |
| Hydrochloric Acid SCHEMBL7363142 | 0.90 | SLC15A1 (0.54) | SLC15A1CTSLERAP1ANPEPERAP2 | |
| Hydrochloric Acid SCHEMBL7363137 | 0.90 | SLC15A1 (0.54) | SLC15A1CTSLERAP1ANPEPERAP2 | |
| Trifluoroacetic Acid SCHEMBL27862747 | 0.85 | CTSL (0.51) | CTSLACEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142668-A1 | CATHEPSIN C INHIBITORS | GLAXO GROUP LIMITED (GB) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142668-A1 | CATHEPSIN C INHIBITORS | CTSE, CTSB, CTSS | SLC15A1 2067/4885CTSL 13/4885ERAP1 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.