Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3271860 | 0.84 | EPHX2 (0.64) | EPHX1SMN1; SMN2TP53TSHREPHX2 | |
| SCHEMBL3271863 | 0.84 | EPHX2 (0.64) | EPHX1SMN1; SMN2TP53TSHREPHX2 | |
| SCHEMBL28249754 | 0.77 | MAPT (0.44) | SMN1; SMN2TSHRMEN1KMT2ACYP19A1 | |
| SCHEMBL5895657 | 0.75 | KMT2A (0.59) | EPHX1SMN1; SMN2TP53MEN1NPC1 | |
| SCHEMBL9112947 | 0.75 | NAPRT (0.54) | EPHX1SMN1; SMN2TP53TSHREPHX2 | |
| SCHEMBL9112963 | 0.75 | NAPRT (0.54) | EPHX1SMN1; SMN2TP53TSHREPHX2 | |
| SCHEMBL4214608 | 0.73 | NAPRT (0.57) | EPHX1SMN1; SMN2TP53TSHREPHX2 | |
| SCHEMBL24202631 | 0.73 | SIRT1 (0.83) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| N-Phenylbenzamide SCHEMBL5402750 | 0.73 | SIRT1 (0.83) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| N-Phenylbenzamide SCHEMBL31966 | 0.73 | SIRT1 (0.83) | SMN1; SMN2MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673936-B1 | Antithrombotic agents | LILLY CO ELI (US) | 2001-02-07 | — | — | EP | disclosed |
| EP-0670310-B1 | Bisulfite adducts of arginine aldehydes useful as thrombin inhibitors and as anticoagulants | LILLY CO ELI (US) | 1998-09-02 | — | — | EP | disclosed |
| EP-0542525-B1 | Antithrombotic agents | LILLY CO ELI (US) | 1998-07-08 | — | — | EP | disclosed |
| US-5484772-A | ARGININE ALDEHYDE COMPOUNDS AS ANTICOAGULANTS OR TREATMENT OF THROMBOEMBOLITIC AGENTS | ELI LILLY AND COMPANY (US) | 1996-01-16 | — | — | US | disclosed |
| EP-0673936-A1 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-09-27 | — | — | EP | disclosed |
| EP-0670310-A1 | Bisulfite adducts of arginine aldehydes useful as thrombin inhibitors and as anticoagulants | ELI LILLY AND COMPANY (US) | 1995-09-06 | — | — | EP | disclosed |
| US-5436229-A | Di- and tripeptides as anticoagulants | ELI LILLY AND COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| US-5416093-A | DIPEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| EP-0542525-A2 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |