Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112947 | 1.00 | NAPRT (0.54) | NAPRTHSD17B10EPHX1SMN1; SMN2TP53 | |
| SCHEMBL3271863 | 0.84 | EPHX2 (0.64) | NAPRTHSD17B10EPHX1SMN1; SMN2TP53 | |
| SCHEMBL3271860 | 0.84 | EPHX2 (0.64) | NAPRTHSD17B10EPHX1SMN1; SMN2TP53 | |
| SCHEMBL10873997 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2MAPTGAAALDH1A1LMNA | |
| SCHEMBL9363961 | 0.79 | SMN1; SMN2 (0.52) | NAPRTHSD17B10EPHX1SMN1; SMN2TP53 | |
| SCHEMBL4214608 | 0.78 | NAPRT (0.57) | NAPRTHSD17B10EPHX1SMN1; SMN2TP53 | |
| SCHEMBL7416207 | 0.75 | EPHX1 (0.52) | NAPRTHSD17B10EPHX1SMN1; SMN2TP53 | |
| SCHEMBL992038 | 0.75 | EPHX2 (0.64) | NAPRTHSD17B10EPHX1SMN1; SMN2TP53 | |
| Acetanilide SCHEMBL28024825 | 0.74 | NAPRT (0.86) | NAPRTHSD17B10EPHX1SMN1; SMN2TP53 | |
| SCHEMBL11717660 | 0.73 | SMN1; SMN2 (0.61) | NAPRTHSD17B10EPHX1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684942-A4 | — | — | 1995-12-27 | — | — | EP | disclosed |
| EP-0684942-A1 | METHOD FOR PREPARING QUINOLINE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | HOECHST CELANESE CORPORATION (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994019312-A1 | METHOD FOR PREPARING QUINOLINE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | HOECHST CELANESE CORPORATION (US) | 1994-09-01 | — | — | WO | disclosed |