Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 4/20 | 0.51 |
| ▸ | AHR | P35869 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PCSK9 | Q8NBP7 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30105384 | 0.85 | LOXL2 (0.60) | LOXL2AHRF2PCSK9 | |
| SCHEMBL3193871 | 0.85 | LOXL2 (0.60) | LOXL2AHRF2PCSK9 | |
| Bromide SCHEMBL30437340 | 0.84 | LOXL2 (0.58) | LOXL2AHRF2PCSK9 | |
| Hydrochloric Acid SCHEMBL27754931 | 0.84 | LOXL2 (0.58) | LOXL2AHRF2 | |
| SCHEMBL6994522 | 0.83 | LOXL2 (0.53) | LOXL2DRD2DRD3AHRF2 | |
| SCHEMBL7502282 | 0.83 | PCSK9 (0.57) | LOXL2AHRF2PCSK9 | |
| SCHEMBL6619148 | 0.83 | PCSK9 (0.57) | LOXL2AHRF2PCSK9 | |
| SCHEMBL28178529 | 0.81 | F2 (0.58) | F2 | |
| SCHEMBL29403791 | 0.81 | LOXL2 (0.69) | LOXL2AHRPCSK9HRH3 | |
| SCHEMBL401081 | 0.81 | LOXL2 (0.69) | LOXL2AHRPCSK9HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106700035-B | A kind of star-like white light polymer of three arm of double-core and preparation method thereof | 福建师范大学 | 2018-10-09 | — | — | CN | disclosed |
| EP-1244652-A1 | 2-(1H-INDOL-3-YL)-2-OXO-ACETAMIDES WITH ANTITUMOR ACTIVITY | Cell Therapeutics Europe S.R.L. (IT) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047916-A1 | 2-(1H-INDOL-3-YL)-2-OXO-ACETAMIDES WITH ANTITUMOR ACTIVITY | NOVUSPHARMA S.P.A. (IT) | 2001-07-05 | — | — | WO | disclosed |
| EP-0640080-B1 | SUBSTITUTED INDOLES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX INC (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0640080-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS. | SYNTEX INC (US) | 1995-03-01 | — | — | EP | disclosed |
| US-5380739-A | Angiotensin II antagonists | SYNTEX (U.S.A.) INC. (US) | 1995-01-10 | — | — | US | disclosed |
| WO-1993023391-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-11-25 | — | — | WO | disclosed |
| US-5212195-A | Substituted indole antagonists derivatives which are angiotensin II | SYNTEX (U.S.A.) INC. (US) | 1993-05-18 | — | — | US | disclosed |