Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | SCARB1 | Q8WTV0 | 5/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403922 | 0.79 | SCARB1 (0.48) | PTGS1PTGS2SCARB1TBXA2RPTGDR | |
| SCHEMBL7408143 | 0.76 | SCARB1 (0.52) | PTGS1PTGS2SCARB1HTR6 | |
| SCHEMBL7409165 | 0.74 | KMT2A (0.48) | HTR6MEN1KMT2A | |
| SCHEMBL7416435 | 0.71 | SCARB1 (0.40) | PTGS1PTGS2SCARB1HTR6SIRT2 | |
| SCHEMBL7413011 | 0.64 | PTGDR2 (0.46) | HTR6TBXA2RPTGDRPTGDR2MEN1 | |
| SCHEMBL7405351 | 0.64 | PTGDR2 (0.43) | PTGDR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7452433 | 0.63 | PTGDR2 (0.45) | HTR6TBXA2RPTGDRPTGDR2MEN1 | |
| SCHEMBL26814906 | 0.62 | KMT2A (0.70) | BCHEMEN1KMT2A | |
| SCHEMBL7408312 | 0.62 | DRD2 (0.53) | HTR6TBXA2RPTGDRPTGDR2MEN1 | |
| SCHEMBL19226482 | 0.62 | SCN1A (0.71) | BCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |