Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCARB1 | Q8WTV0 | 6/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PARG | Q86W56 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407550 | 0.75 | PKM (0.39) | SCARB1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL7403922 | 0.74 | SCARB1 (0.48) | SCARB1PTGS1PTGS2SIRT2PARG | |
| SCHEMBL7408143 | 0.74 | SCARB1 (0.52) | SCARB1PTGS1PTGS2HTR6 | |
| SCHEMBL7405351 | 0.65 | PTGDR2 (0.43) | ALDH1A1MEN1LMNACYP2D6KMT2A | |
| SCHEMBL2072991 | 0.61 | MAPT (0.59) | ALDH1A1MEN1LMNACYP2D6KMT2A | |
| SCHEMBL12496253 | 0.60 | ALDH1A1 (0.46) | PTGS2ALDH1A1LMNACYP2D6KMT2A | |
| SCHEMBL15899549 | 0.59 | SCARB1 (0.65) | SCARB1PTGS1PTGS2ALDH1A1MEN1 | |
| SCHEMBL2266114 | 0.59 | LMNA (0.45) | PTGS1PTGS2ALDH1A1MEN1LMNA | |
| SCHEMBL25424268 | 0.59 | PARG (0.47) | ALDH1A1MEN1LMNACYP2D6KMT2A | |
| SCHEMBL7414173 | 0.59 | HTR6 (0.50) | CYP2D6HTR6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |