Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.60 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413028 | 0.89 | OPRM1 (0.57) | OPRM1TMEM97HTR2AHTR2CHTR7 | |
| SCHEMBL7419477 | 0.86 | HTR2A (0.48) | OPRM1TMEM97HTR2A | |
| SCHEMBL28781770 | 0.79 | OPRM1 (0.80) | OPRM1TMEM97 | |
| SCHEMBL9330147 | 0.76 | HTR2A (0.87) | HTR2AHTR2CHTR7 | |
| SCHEMBL28781746 | 0.75 | OPRM1 (1.00) | OPRM1TMEM97 | |
| SCHEMBL7409872 | 0.74 | HTR2A (0.43) | OPRM1TMEM97HTR2A | |
| SCHEMBL7412596 | 0.74 | HTR2A (0.41) | OPRM1TMEM97HTR2AHTR2CHTR7 | |
| SCHEMBL28781760 | 0.73 | OPRM1 (1.00) | OPRM1TMEM97 | |
| SCHEMBL9328582 | 0.73 | HTR2A (0.87) | TMEM97HTR2AHTR2CHTR7 | |
| SCHEMBL16056383 | 0.72 | HTR2A (0.54) | OPRM1TMEM97HTR2AHTR2CHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |