Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416616 | 0.86 | OPRM1 (0.60) | HTR2AOPRM1TMEM97 | |
| SCHEMBL7417747 | 0.82 | HTR2A (0.48) | HTR2ADRD2TMEM97 | |
| Oxalic Acid SCHEMBL10461397 | 0.78 | KDM4E (0.58) | HTR2ADRD2KDM4EALDH1A1LMNA | |
| SCHEMBL10559724 | 0.77 | HTR2A (0.56) | HTR2ADRD2TMEM97 | |
| SCHEMBL7413028 | 0.76 | OPRM1 (0.57) | HTR2AOPRM1TMEM97 | |
| SCHEMBL10560937 | 0.76 | HTR2A (0.55) | HTR2ADRD2TMEM97 | |
| Oxalic Acid SCHEMBL10460865 | 0.76 | KMT2A (0.56) | HTR2ADRD2KDM4EALDH1A1 | |
| Fumaric Acid SCHEMBL10461367 | 0.75 | DRD2 (0.51) | HTR2ADRD2 | |
| Fumaric Acid SCHEMBL10461365 | 0.75 | DRD2 (0.51) | HTR2ADRD2 | |
| SCHEMBL7413839 | 0.75 | HTR2A (0.54) | HTR2ADRD2ALDH1A1LMNATMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |