Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144289 | 0.61 | HTR1A (0.39) | — | |
| SCHEMBL9199699 | 0.59 | NOTUM (0.51) | KDM4EHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL18269285 | 0.57 | HSD17B10 (0.44) | HSD17B10CASP1CASP7KDM4EHPGD | |
| SCHEMBL9202117 | 0.57 | HPGD (0.36) | HSD17B10CASP1KDM4EHPGDALOX15 | |
| SCHEMBL12923725 | 0.56 | KDM4E (0.41) | HSD17B10CASP1CASP7KDM4EHPGD | |
| SCHEMBL16772300 | 0.56 | MTNR1A (0.38) | HSD17B10KDM4EHPGDALOX15ALDH1A1 | |
| SCHEMBL16656118 | 0.56 | HSD17B10 (0.42) | HSD17B10CASP1CASP7KDM4EHPGD | |
| SCHEMBL14514307 | 0.56 | HSD17B10 (0.39) | HSD17B10CASP1CASP7KDM4EHPGD | |
| SCHEMBL16441211 | 0.56 | CASP1 (0.42) | HSD17B10CASP1CASP7KDM4EHPGD | |
| SCHEMBL14336543 | 0.56 | EGFR (0.48) | HSD17B10CASP1KDM4EHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994004533-A1 | CONDENSED INDOLE DERIVATIVES AS 5HT2C AND 5HT2B ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-03-03 | — | — | WO | disclosed |