Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 7/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.36 |
| ▸ | NPY1R | P25929 | 5/20 | 0.36 |
| ▸ | NPY2R | P49146 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937672 | 0.91 | EPHX2 (0.37) | NPY4RNPY5RNPY1RNPY2RALOX15 | |
| SCHEMBL13363649 | 0.76 | NPY4R (0.42) | NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL19227721 | 0.74 | EPHX2 (0.46) | NPY4RNPY5RNPY1RNPY2RMEN1 | |
| SCHEMBL7099770 | 0.73 | ITGB3 (0.47) | — | |
| SCHEMBL20375836 | 0.71 | SMN1; SMN2 (0.46) | ALOX15MEN1CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL16359252 | 0.71 | NPY4R (0.52) | NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL15185892 | 0.71 | NPY4R (0.44) | NPY4RNPY5RNPY1RNPY2RALOX15 | |
| SCHEMBL20244908 | 0.70 | EPHX2 (0.36) | — | |
| SCHEMBL20244985 | 0.70 | EPHX2 (0.36) | — | |
| SCHEMBL437938 | 0.70 | SMN1; SMN2 (0.50) | ALOX15MEN1CYP1A2KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097127-A1 | DIACYLHYDRAZINE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GmbH (DE) | 2001-05-09 | — | — | EP | claimed |
| WO-2000003973-A1 | DIACYLHYDRAZINE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GMBH (DE) | 2000-01-27 | — | — | WO | claimed |