Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411442 | 0.85 | MGLL (0.35) | MGLLCYP4F2CYP4A11 | |
| SCHEMBL7408578 | 0.72 | CHRNB2 (0.41) | CHRNB2CHRNA4 | |
| SCHEMBL25384115 | 0.72 | NQO1 (0.48) | — | |
| Hydrochloric Acid SCHEMBL8440713 | 0.71 | CHRNB2 (0.56) | CHRNB2CHRNA4 | |
| SCHEMBL8552724 | 0.70 | CHRNB2 (0.33) | CHRNB2CHRNA4CYP4F2CYP4A11 | |
| SCHEMBL20411522 | 0.68 | CA12 (0.40) | — | |
| SCHEMBL2939725 | 0.67 | ACACB (0.38) | — | |
| SCHEMBL6657708 | 0.67 | CHRNB2 (0.51) | CHRNB2CHRNA4 | |
| SCHEMBL7412587 | 0.66 | CHRNB2 (0.42) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL2134343 | 0.66 | ACACB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047690-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 2000-11-02 | — | — | EP | claimed |
| WO-1999032480-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1999-07-01 | — | — | WO | claimed |